Another note to consider is adding columns in specific locations as you go:

Another standard solution to is to pair the pd.drop() and the pd.insert() methods. The main limitation of this option is that it only works when moving one column at a time to a specific location.
Reordering Pandas DataFrame Columns: Thumbs Down On Standard Solutions
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Adam Ross Nelson
Adam Ross Nelson
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Feb 4, 2021
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Another note to consider is adding columns in specific locations as you go:
Example
`df.insert(0, 'new', np.random.random(5))`
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Written by Adam Ross Nelson
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